GAMMA GLOBULIN COMPLEXES IN RHEUMATOID ARTHRITIS AND CERTAIN OTHER CONDITIONS
نویسندگان
چکیده
منابع مشابه
Gamma Globulin Complexes in Rheumatoid Arthritis
Recent studies have demonstrated that the factors responsible for the various serological reactions currently employed for the diagnosis of rheumatoid arthritis represent macroglobulins which, in the isolated state, have a corrected sedimentation coefficient of approximately 19S (1-5). In serum and plasma, these proteins exist as complexes with low molecular weight y-globtulins and show a highe...
متن کاملIgG anti-IgG antibodies in rheumatoid arthritis and certain other conditions.
Rheumatoid factor (Rose, Ragan, Pearce, and Lipman, 1948), known to be a frequent finding in the sera of patients with rheumatoid arthritis, was thought to be an unusual antibody in that it occurred in the 19S and 22S forms (Franklin, Holman, Muller-Eberhard, and Kunkel, 1957) without showing evidence for 7S analogues. The activity of this antibody appeared to be directed against gammaglobulin....
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Background: Changes in patients’ bone mineral density (BMD) is one of the problems in patients with rheumatoid arthritis, which can be due to the use of corticosteroid drugs to reduce patients' symptoms or due to the aging process in patients. In this study, we decided to compare BMD in patients with psoriatic arthritis and rheumatoid arthritis. Methods: This study as a cross-sectional descrip...
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The effect of highly purified rheumatoid factor on the precipitin reactions of various antigen-antibody systems was determined. The amount of nitrogen precipitated was increased over a broad range when the factor was added to ovalbumin, human albumin, or human gamma globulin, and the corresponding rabbit antibodies. In the zone of antigen excess, soluble antigen-antibody complexes were precipit...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1961
ISSN: 0021-9738
DOI: 10.1172/jci104224